Cardiorespiratory fitness is widely recognized as a major component of overall physical well-being. Direct measurement of maximal oxygen uptake (VO2max) is the single best measure of such fitness, but direct measurement is time-consuming and expensive. It is therefore desirable to have a prediction equation for VO2max in terms of easily obtained quantities. A sample is taken and variables measured are age (years), time necessary to walk 1 mile (mins), and heart rate at the end of the walk (bpm] in addition to the VO2 max uptake. The following output is from a multiple regression. Interpret the slope of the time variable. Predictor t-ratio P Constant 16.099 24 601 0. 237 1.08 0.3031 HR. -0.193 0 . 292 -O.TE 0-4809 -3. 806 0 . 429 -1.14 O.001637 8 07.217 R-87 - 68.524 R-541411) = 59.914 Analysis of Variance SOURCE OF HE Regression 1247 . 11 415-T 0. 004189 Error 11 972. 9 Total 14 1820. 01 () 1) We do not have enough information to say. 2) When time increases by 1 minute, VO2 decreases by 2.606 L/min, holding all other variables constant. 3) When time decreases by 1 minute, VO2 decreases by 2.606 L/min, holding all other variables constant. (4) When time decreases by 2.606 minutes, VO2 increases by 1 L/min, holding all other variables constant. (5) When time increases by 1 minute, VO2 increases by 2.606 L/min, holding all other variables constant