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The syntheses of aziridine, azetidine and pyrrolidine are shown in Figure 4. a. Reaction 1: H2N. Br Aziridine NH Reaction 2: Br Azetidine Reaction

  

The syntheses of aziridine, azetidine and pyrrolidine are shown in Figure 4. a. Reaction 1: H2N. Br Aziridine NH Reaction 2: Br Azetidine Reaction 3: H,N. Br Pyrrolidine Figure 4 (1) Classify the above reactions according to Baldwin rules and explain the nomenclature you use. (ii) Identify which reactions are favoured or disfavoured and explain your answer. (iii) Consider the rate of the reactions shown in Figure 4. Reaction 3 takes place - 1.4 x 10 times faster than Reaction 1 and 1 x 10 times faster than Reaction 2. Explain these results taking into account the free energy involved in the reactions. Draw the structure of compound N and discuss the mechanism of the reaction of compounds L and M to give compound N. What is the name of this reaction? b. DABCO C12H1202

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