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Coat color in mice is controlled by two genes. The M/m gene encodes an enzyme that makes a black pigment while A/a makes yellow

 

Coat color in mice is controlled by two genes. The M/m gene encodes an enzyme that makes a black pigment while A/a makes yellow pigment. The dominant M allele results in normal black pigment production, while recessive m produces less pigment. Combined with the wild-type a allele of the other gene, M results in a brown mouse while mm produces a tan-colored mouse. The dominant A allele produces excessive yellow pigment, producing a yellow mouse regardless of M or m genotype. In a dihybrid cross, we expect [Select] dominant alleles (M_A_), while [Select] of the offspring to have both have a dominant allele of one gene have and recessive for the other (M_aa & mmA_). The remaining [Select] genotype mmaa. Given how these genes interact, the overall phenotype ratio from this cross will be [Select] This is an example of [Select]

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