Question
Compounds 1 and 3 both bind to the same pocket of the same target protein. Compare the features of the two structures, and use this
Compounds 1 and 3 both bind to the same pocket of the same target protein. Compare the features of the two structures, and use this to explain the term bioisosteres? (3 marks)
NH2 1 3
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Chemistry The Central Science
Authors: Theodore Brown, Eugene LeMay, Bruce Bursten, Catherine Murphy, Patrick Woodward
12th edition
321696727, 978-0132175081, 978-0321696724
