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Consider the data again: Study Sample Size Relative Risk p-value 95% CI A 100 2.0 0.10 0.8 - 4.2 B 500 2.0 0.06 0.9 -

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Consider the data again: Study Sample Size Relative Risk p-value 95% CI A 100 2.0 0.10 0.8 - 4.2 B 500 2.0 0.06 0.9 - 3.3 C 1000 3.5 0.02 2.6 - 4.5 D 2000 3.0 0.015 2.2 - 3.5 E 2500 3.2 0.001 2.8 - 3.6 Are the confidence intervals consistent between studies? Do they indicate a consistent association between exposure and disease? O Some of the studies are statistically significant and some are not; therefore no association can be surmised O Even though there is varying significance, the range of confidence intervals has great overlap and indicates an association between exposure and disease The range of confidence intervals indicates that the point estimate is 1.4 None of the above are true

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