Answered step by step
Verified Expert Solution
Link Copied!
Question
1 Approved Answer

Consider the following AML acute myelogenous leukemia data. The study was conducted by Embury et al. (1977) at Stanford University. Group Length of complete

Consider the following AML – acute myelogenous leukemia data. The study was conducted by Embury et al. (1977) at Stanford University.

Group

Length of complete remission (in weeks)

Maintained

9,13,13+,18,23,28+,31,34,45+,48,161+

Nonmaintained

5,5,8,8,12,16+,23,27,30,33,43,45

  1. Produce tables for KM estimates to each group. Then plot KM curves for each roup on the same graph. Comment on how these curves compare with each other.
  2. Use R to check your answers.
  3. Use (i) the Gehan’s Generalised Wilcoxon Test (ii) the Cox-Mantel Test and (iii) the logrank test to compare two survival curves in part (a). What is your null hypothesis and how is the test statistic distributed under this null hypothesis? What are your conclusions from the test?
  4. Use excel and R to check your results.

Step by Step Solution

There are 3 Steps involved in it

Step: 1

C Descmi be kaplay Meier estimator f survival fimation sit for a data begi with h... blur-text-image
Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image_2

Step: 3

blur-text-image_3

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Practicing Statistics Guided Investigations For The Second Course

Authors: Shonda Kuiper, Jeff Sklar

1st Edition

321586018, 978-0321586018

More Books

Students explore these related Accounting questions