Answered step by step
Verified Expert Solution
Link Copied!

Question

00
1 Approved Answer

Consider the following dynamic model for sustained oscillations in yeast glycolysis: d G d t = V i n - k 1 G A =

Consider the following dynamic model for sustained oscillations in yeast glycolysis:
dGdt=Vin-k1GA=f1(G,A)
dAdt=2k1GA-kpAKm+A=f2(G,A)
where G and A are the intracellular concentrations of glucose and ATP, respectively, Vin=0.36 is the constant flux of glucose into the yeast cell, k1=0.02 is an enzyme activity, and the parameters kp=6.0 and Km=13.0 determine the kinetics of ATP degradation.
(a) Show that the given parameter values produce a single steady-state solution ?bar(G) and ?bar(A).
(b) Find the linearized model at this steady-state point dxdt=Ax where x=[G'A']T.
(c) Determine the stability of the steady state by computing the eigenvalues of the A matrix.
image text in transcribed

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access with AI-Powered Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Students also viewed these Chemical Engineering questions