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Consider the production of penicillin (C16H18O4N2S, MW=334) where glucose (C6H12O6, MW=180) is used as Carbon source, ammonia (NH3, MW=17) as Nitrogen source and phenylacetic acid

Consider the production of penicillin (C16H18O4N2S, MW=334) where glucose (C6H12O6, MW=180) is used as Carbon source, ammonia (NH3, MW=17) as Nitrogen source and phenylacetic acid (C8H8O2, MW=136) is added as precursor by using Penicillium chyrsogenum. The balanced reaction for overall synthesis is:

1.67 C6H12O6 +2 NH3 + 0.5O2 + H2SO4 + C8H8O2 C16H18O4N2S + 2CO2 + 9 H2O

What is the maximum theoretical yield of penicillin from phenylacetic acid in g/g in this system?

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