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Cooling requirements in a fermenter: You are responsible for the transfer of a batch fermentation process from a pilot plant in Bethlehem, PA to the
Cooling requirements in a fermenter: You are responsible for the transfer of a batch fermentation process from a pilot plant in Bethlehem, PA to the commercial manufacturing site in the tropics. The organism is a strain of E. coll, which has the composition CH1.8O0.53N0.15. Your pilot studies indicate that the maximum rate of heat formation due to cell metabolism is 105kJ/h. Additionally, the rate of mechanical heat generation is 105kJ/h. The fermentation process is run at 32C. You are also given information about the commercial site: - The fermenter is a jacketed vessel with a maximum working volume of 1000L. The vessel radius, not including the jacket, is 0.45m. - The temperature in the vessel will be maintained by running city water through the jacket. Depending upon the water pressure, the flow rate of the water ranges from 50 to 60 gal/min. Depending on the time of the year, the inlet temperature of the water ranges from 22C to 26C. - The heat transfer coefficient of the vessel is 250W/(m2C) Given the information about the process, fermentation vessel, and water, can this process be run at the commercial site? State your assumptions and show your calculations. You may need to look up some of the information needed to solve this
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