Corporation itself is young and involved. Hyten has enjoyed a period of continuous growth over the past fifteen years as a result of careful planning and having the right people in the right positions at the right time. This is emphasized by the fact that within five years of joining Hyten, every major manager and division head has been The Automotive Components Division 23 Exhibit I. Organizational chart of the automotive division, Hyten Corporation General Manager Operations Comptroller Director of Engineering Director of Business Development Director of MIS Director of Personnel Director of Marketing Manager of Purchasing Manager of Quality and Reliability Manager of Manufacturing Engineering Plant Manager of Plant A Plant Manager of Plant B Plant Manager of Plant C President Automotive Division 1321.ch02 11/3/05 9:09 AM Page 23 promoted to more responsibility within the corporation. The management staff of the Automotive Components Division has an average age of forty and no one is over fifty. Most of the middle managers have MBA degrees and a few have Ph.D.s. Currently, the Automotive Components Division has three manufacturing plants at various locations throughout the country. Central offices and most of the nonproduction functions are located at the main plant. There has been some effort by past presidents to give each separate plant some minimal level of purchasing, quality Hyten Company was founded in 1982 as a manufacturer of automotive components. During the Gulf War, the company began manufacturing electronic components for the military. After the war, Hyten continued to prosper. Hyten became one of the major component suppliers for the Space Program, but did not allow itself to become specialized. When the Space Program declined, Hyten developed other product lines, including energy management, building products, and machine tools, to complement their automotive components and electronics fields. Hyten has been a leader in the development of new products and processes. Annual sales are in excess of $600 million. The Automotive Components Division is one of Hyten's rapidly expanding business areas

1 As a third-year medical student in Russia I am researching 'the role of proteolytic enzymes and their inhibitors in lung pathology'. Can you explain how proteolytic enzymes function in the normal lung?

2 Bronchiectasis is given as one of the causes of bronchial breath sounds. This is difficult to comprehend. Could you explain the mechanism of bronchial breath sounds more clearly?

3 I have been taught to examine vocal resonance by asking the patient to say 'ninety-nine' while auscultating. I listen for a louder 'ninety-nine' over an area of consolidation and more quiet sounds with effusion. Is this right?

4 What role does bupropion play in giving up smoking?

5 The clinical signs and symptoms of rhinitis are very similar to those of the common cold (influenza). How do I differentiate between the two?

6 What is the advantage of the drugs des-loratidine and levo-cetirizine over their parent compounds? Are they safe in pregnancy and lactation?

7 What are the differences between acute bronchitis and pneumonia? Are both diseases caused by infection?

8 1. If a patient with chronic bronchitis develops obstructive jaundice and Escherichia coli biliary sepsis, should the routine administration of oral steroids (e.g. prednisolone) be suspended until liver function improves? 2. Are there any adverse reactions that preclude the concurrent use of steroids while the patient is treated with IV ciprofloxacin, gentamicin, metronidazole and cefuroxime?

9 Robbins Basic Pathology mentions that in patients with chronic obstructive pulmonary disease (COPD), the forced ventilation capacity (FVC) is either normal or slightly increased! I just can't justify that. I mean it should decrease. And this is exactly what is mentioned in your book. I couldn't contact the authors of that book so I decided to ask you whether there is actually a situation in which the FVC in COPD patients might increase?

10 Is there any obstructive pulmonary condition in which there might be an increase in FVC? If so by what mechanism?