Question: Dihydrodipicolinate synthase ( DHDPS ) ( EC 4 . 3 . 3 . 7 ) catalyses the aldol - like condensation of pyruvate and L

Dihydrodipicolinate synthase (DHDPS)(EC 4.3.3.7) catalyses the aldol-like condensation of
pyruvate and L-aspartate beta semi-aldehyde (S-ASA). It is an enzyme involved in the lysine
biosynthetic pathway of procaryotes, some Phycomycetes and higher plants. Since this pathway is
not present in animals, pathway members such as DHDPS have become attractive targets for
rational antibiotic and herbicide drug design.

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