DISEASE/DISORDERS 1. Patients with COPD (Chronic Obstructive Pulmonary Disease) may develop respiratory acidosis. Explain how COPD causes respiratory acidosis and why breathing rate is elevated in COPD patients with respiratory acidosis. 2. You can only hold your breath for a limited period of time before you involuntarily begin breathing again. Describe feedback mechanisms that result in involuntary breathing. 3. Anxiety can cause hyperventilation. Explain how anxiety can cause hyperventilation and how hyperventilation causes respiratory alkalosis. 4. Patients with uncontrolled diabetes can develop metabolic acidosis. Explain how uncontrolled diabetes causes metabolic acidosis.