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Do any factors appear to be related to the risk of any recurrence of disease to bladder-only recurrence in Table 4? Table 4 - Multivariable

Do any factors appear to be related to the risk of any recurrence of disease to bladder-only recurrence in Table 4?

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Table 4 - Multivariable Cox regression models predicting disease recurrence (any recurrence and bladder-only recurrence) in patients treated with radical nephroureterectomy for upper tract urothelial carcinoma Any recurrence Hazard ratio Bladder-only recurrence 95% CI p value Age, per 10 yr Hazard ratio 95% CI 0.87 p value 0.72-1.05 ASA 0.15 0.84 0.68-1.04 0.11 Reference Reference 1.03 0.67-1.57 Reference Reference 0.9 0.86 Pathologic stage 0.53-1.41 0.6 SPT1 Reference PT2 Reference 1.45 0.002 0.82-2.56 Reference Reference 0.6 2PT3 2.31 1.44-3.70 1.39 0.75-2.57 1.06 0.58-1.93 Pathologic grade Low Reference High Reference 1.39 Reference 0.74-2.62 Reference 0.3 1.27 0.67-2.42 0.5 Nodal status Not done Reference Reference 0.3 Reference Negative Reference 0.04 0.66 0.40-1.10 0.65 Positive 0.80 0.37-1.14 0.40-1.63 0.25 0.08-0.74 Pathologic CIS NO Reference Reference Reference Reference Yes 1.00 0.64-1.57 0.99 0.93 0.55-1.57 0.8 Previous bladder cancer 2 Reference Reference Reference Reference 1.04 0.68-1.58 0.9 1.18 0.72-1.91 Surgical approach ORA Reference Reference Reference Reference LRN 0.88 0.57-1.38 g 0.78 0.46-1.34 ASA - American Society of Anesthesiologists; CI = confidence interval; CIS - carcinoma in situ; LRN - laparoscopic radical nephroureterectomy; ORN - oper radical nephroureterectomy. IBC, which is a known risk factor for bladder recurrence; were similar between the LRN and ORN groups, avoiding vever, we identified exactly the same proportion of selection bias commonly seen with the introduction of

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