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e. Losartan (structure below) contains a tetrazole functional group. ci OH N-NH losartan i. For which functional group is a tetrazole ring a bioisostere? State

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e. Losartan (structure below) contains a tetrazole functional group. ci OH N-NH losartan i. For which functional group is a tetrazole ring a bioisostere? State ONE physiochemical similarity and ONE difference. (3 marks) ii. Draw the predominant structure of losartan at pH 7.4, showing the resonance structures as appropriate. (2 marks)

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