Enzyme (E) is a catalyst that performs the action of accelerating the rate of various biological reactions occurring in cells, and is a catalyst with excellent specificity.

Various factors affect the activity of the enzyme, and the pH of the solution changes the physicochemical properties of the substrate S binding to the active site of the enzyme, and thus the activity of the enzyme has a great influence.

Answer the following questions about when an enzyme that is activated under low pH conditions in a solution acts to convert the substrate into product (P).

(a) Express the mechanism of action of this enzyme with reaction constants for each step.

(b) Derive the Michalis-Menten velocity equation based on the fast equilibrium assumption in the reaction mechanism of (a).