Epidemiology question:

By using the data from the yale new haven hospital, try to estimate the proportion of endometrial cancer diagnosis during life. Consider the two types as: Typa A being endometrial cancer diagnosed during life and type B which is not diagnosed during life.

Use the equation: P = (I x D) where p is the prevalence, I is the incidence, D is the duration

1. Assume that among women who get to age 45, the average age at death will be 80; that is, they are at risk of developing endometrial cancer for 35 years. What proportion of women who achieve age 45 develop a Type A endometrial cancer?

2. Among 10,000 decedent women, 22 harbor an undiagnosed (Type B) endometrial cancer. What is the proportion of women who develop endometrial cancer of either type at some point in their life? (Show your work)

3.Type A comprises what proportion of all endometrial cancer? Type B comprises what proportion?

NECROPSY DETECTION OF ENDOMETRIAL CANCER IN WOMEN AGED 45 YEARS OR MORE WITH INTACT UTERI Yale- New Haven Hospital (191878) Massachusetts General Hospital (1952-78) 4636 15 10 4462 27 14 Eligible necropsy population Patients with endometrial cancer Patients whose cancer was first diagnosed at necropsy Unsuspected cancers (%) Rate of endometrial cancer first detected at necropsy (per 10 000) Rate of detected endometrial cancer estimated by CSTR (per 10 000) 67% 22 52% 31 4.7 (193574) 5.5 (195074) NECROPSY DETECTION OF ENDOMETRIAL CANCER IN WOMEN AGED 45 YEARS OR MORE WITH INTACT UTERI Yale- New Haven Hospital (191878) Massachusetts General Hospital (1952-78) 4636 15 10 4462 27 14 Eligible necropsy population Patients with endometrial cancer Patients whose cancer was first diagnosed at necropsy Unsuspected cancers (%) Rate of endometrial cancer first detected at necropsy (per 10 000) Rate of detected endometrial cancer estimated by CSTR (per 10 000) 67% 22 52% 31 4.7 (193574) 5.5 (195074)