feedback on this Quality of evidence refers to the degree of certainty that the estimate of an effect is correct and how much confidence we can have to recommend something. There are multiple factors that go into determining the quality of evidence. According to GRADE, the quality of evidence can be high, moderate, low, or very low. Careful consideration must be taken when determining the quality of evidence based on specific criteria. Quality of evidence is the same thing as certainty of evidence . When the quality or certainty of evidence is low or very low, recommendations are more likely to be weak as opposed to when the GRADE score is high or moderate