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For a vertebrate neuron you are studying at 3 0 oC , you have measured the following intracellular and extracellular concentrations ( concentrations are in

For a vertebrate neuron you are studying at 30 oC , you have measured the following intracellular and extracellular concentrations (concentrations are in mM),
although unfortunately you were unable to make accurate measurements of [Na+]s:
[K+] in =145.5[K+] out =4.2
[Mg2+] in =2.2[Mg2+] out =5.4
[Na+] in =?[Na+] out =?
[Cl-] in =7.0[Cl-] out =156.0
[A-] in =147.4[A-] out =0
You determined that the membrane is impermeable to Mg 2+ and A-
. You have also determined that at rest, the permeability to K+ is 50 times the permeability to Na +, and the permeability to Cl- is twice the permeability to Na+.
(a) Assuming the above is a complete list of solutes present in the intracellular and
extracellular solutions, calculate [Na+] in and [Na+] out .
(b) Calculate the membrane resting potential, Vrest .
(c) At the Vrest you calculated for part (b), what is the driving force on the chloride
ions (DFCl-)?
(d) In which direction would the Cl - ions carry current at Vrest ? In which direction
would Cl - ions move?Steps for Posting a question

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