For this question, please document step-by-step how you are solving the problem as you do it. Include the steps you are taking and why, what you are thinking about as you solve the problem, and how you reached your final answer. Please number each of these steps. Below is an example of how to do this. Example of how to Document your Problem Solving: Question: A double-stranded piece of DNA has 30% adenine. What percentage of the molecule is guanine? Documented Problem Solving Answer Example: 1. Read the problem. 2. Know that I am thinking about DNA composition. 3. Re-read the problem and note that I'm given adenine (A) %, and I need to determine guanine (G) %. 4. From class, I learned that A binds T, and G binds C. 5. I draw a piece of double-stranded DNA with A binding thymine (T) and G binding cytosine (C) so that I can visualize and make sure that I remembered correctly 6. Because of this binding, there should be the same amount of A as T and the same amount of G as C. 7. Therefore, there should be 30 % A and the same amount, 30 % , T 8. I add 30% A and 30 % T together to account for 60 % of the nucleotides. 9. There is 100% total of A, G, T, and C, so 100-60%-40% will be the remaining percent. 10. Half of 40% is 20 % , so there will be 20 % of G and 20 % of C. 11. FINAL CONCLUSION: 20% of the molecule will be guanine. Extra Credit Question for You to Solve (while documenting step-by-step): You are studying a mutation in the HexA gene that causes the autosomal recessive disease Tay Sachs. The first image below shows the amount and size of HexA mature mRNA found in a sample. The second image below shows the amount and size of HexA protein. The thickness of the band indicates relative amount of mRNA and protein, respectively. You examine mRNA and protein from Jamie, who does not have Tay Sachs, and from Alice, who has the disease. What is one possible mutation of the HexA gene that could have caused this disease in Alice? mRNA Jamie Alice 20 kb mRNA size 10 kb Protein Jamie Alice 250 kDa Protein size 25 kDa