1. Forty-five patients with hematogenous candidiasis who received fluconazole (200 to 600 mg/day) in an open-label trial at the University of Texas M. D. Anderson Cancer Center, Houston, Texas, between February 1990 and June 1992 were matched to 45 patients treated with amphotericin B (0.3 to 1.2 mg/kg/day) for the same diagnosis. Criteria for matching included the following prognostic variables at the initiation of therapy: pneumonia, neutropenia (<1,000 cells/mm3), number of positive blood cultures before therapy, infecting candida species, underlying disease, and the simplified acute physiology score. Patients were followed up for the mortality outcome.

1. Specify the study population, outcome, and exposure from the above research study information
2. Specify which measure/descriptive statistics is suitable for summarizing the outcome given the nature of the follow-up study.
3. Specify the type of design as paired or unpaired
4. Specify an alternative way to match so many variables