Healthy ' 111 _ 2,350 3,300 a. What is the most appropriate relative measure of association to use in this study? b. Comparing the study population with and without misclassification using this measure of association, is there evidence of information bias? c. If there is evidence of information bias, is it differential or non differential? Explain why by comparing the errors in misclassification of disease between the exposed and unexposed. d. If there is information bias, is it towards or away from the null? Why? 3. In a case-control study, exposure status was misclassified as follows: Study Population without Misclassification I I Cases Controls ' | Exposed | 500 500 \\ IUnexposed | 250 1,000 \\ Study Population with Misclassification 1,250 a. What is the most appropriate relative measure of association to use in this study? b. Comparing the study population with and without misclassification using this measure of association, is there evidence of information bias? c. If there is evidence of information bias, is it differential or non- differential? Explain why by comparing the errors in misclassication of exposure between the cases and controls. :1. If there is information bias, is it towards or away from the null? Why