Hello i neeed help with those stat problems
Treatment 1 week CRP 52 64 60 LEGEND 14 NHO 60 13 72 65 34 H H H H P P P P P P P O O O O O O O O o o o o o o o o o o o o o o o o o oooooo0 0 74 35 44 37 71 77 110 5020 15 NN NN NN NN NN NN NN NN NN NN NN NNNAHPPPPPPPPPPPPPPPPPP 17 N 34 94 34 90110 NNN NN NN NN NNConservative Management (control) Antibiotic group Surgical intervention group\fPart 2 - Application Using Statistical Software (15 marks) Scenario: A researcher is interested in exploring the most effective method for treating osteomyelitis (infection of the bone). To study this, they conduct a series of experiments. First, they randomize 100 patients exhibiting osteomyelitis symptoms into one of 3 groups: a conservative management group (i.e., no treatment = 0), an antibiotic treatment group = 1, and a surgical treatment group = 2. One week later, they asked patients to come back in and measure their C reactive protein (CRP), which is a marker of systemic inflammation. High CRP values suggest infection. Question #1: Does CRP differ between the three intervention groups? (5 marks) Answer the question using the M05_ Homework Data file (Dataset1) in the resources section. A) State your hypothesis statements and significance level. B) Describe the statistical analysis you chose, why you chose that test, and what the grouping factor and levels are. C) Describe the assumptions of this statistical test. Describe how you tested the assumptions and provide any relevant statistical output. D) Use SPSS to conduct the analysis, report your findings including the test statistic and p value. Include pairwise comparisons tests, if applicable. E) State whether you would reject or retain the null hypothesis in this scenario and provide a brief summary of the findings. 2Scenario: Based on the findings from study 1, the researchers decide to conduct a second study that explores a patient reported outcomes measures (PROMs). They take another 100 patients from the clinic, once again randomize each patient into one of 3 groups: a conservative management group (i.e., no treatment = D), an antibiotic treatment group = l, and a surgical treatment group = 2. Six months following the interventions they collect the patients' self- reported quality of life, on a validated scale of 1 to 5. Question #2: Does quality of life differ between the three intervention groups? (5 marks) Answer the question using the M05_ Homework Data le {DatasetZ} in the resources section. A) State your hypothesis statements and signicance level. B) Describe the statistical analysis you chose, why you chose that test, and what the grouping factor and levels are. C) Describe the assumptions of this statistical test. Describe how you tested the assumptions and provide any relevant statistical output. D) Use SPSS to conduct the analysis, report your findings including the test statistic and p value. Include painnrise comparisons tests, if applicable. E) State whether you would reject or retain the null hypothesis in this scenario. Module 05 Homework Problems Note: Please check the assignment description for your submission requirements. Part 1 - Consolidating Concepts {5 marks) 1. Describe when you would use an Analysis of Variance, and how it differs from other statistical tests you learned about in Module 03 and 04, such as 2 tests, t tests, and chi square tests. (1 mark) 2. Describe between group variation, within group variation, and how they relate to the F ratio. (2 marks) 3. Describe between and within subject grouping factors, what they are, and when they are used in relation to one-way and repeated measures ANOVAs. (2 marks) Continue to the next age for Part 2. Scenario: Based on the findings from the first two studies, the researchers decide to conduct a third study that explores how clinical markers of osteomyelitis change over time in the conservative management group. They take 37 patients who have been scheduled for conservative management and collect their CRP at baseline, 6 months, and 12 months later. Question #3: Does CRP change over time? (5 marks) Answer the question using the M05_ Homework Data file (Dataset 3) in the resources section. A) State your hypothesis statements and significance level. B) Describe the statistical analysis you chose, why you chose that test, and what the grouping factor and levels are. C) Describe the assumptions of this statistical test. Describe how you tested the assumptions and provide any relevant statistical output. D) Use SPSS to conduct the analysis, report your findings including the test statistic and p value. Include pairwise comparisons tests, if applicable. E) State whether you would reject or retain the null hypothesis in this scenario, provide a brief summary of findings, including a graph with the results. 4
