Hello there I would really appreciate your assistance with these questions. Thank you

Colchicine, extracted from a plant known as the autumn crocus, has been used for many years as a treatment for gout. A synthetic appraoch to colchicine is outlined below. OME OMe Meo. Me. . .CO Me CN Meo Me0 MeOC NC OMe OMe OME Meo. Me (iv) Meo pH 5 'N H Meo Meo Meo MeOC (v) .CN : H30* NC 3 OMe OMe Meo. Meo Meo Me01 CO Me 5 CN (a) Provide the reagents and the conditions for transformation (i). This may involve more than one step (b) Transformation (ii) allows for the formation of a 7-membered ring compound 1. Provide the reagent(s) required and a mechanim for this transformation. (c) Explain why the product 1 is formed under the reaction conditions you chose rather than 2 (d) Provide the reagents and conditions required for the transformation of 1 into 3. Give a detailed mechanism for this process. (e) As shown above compound 3 can undergo reaction to afford 4. Provide mechanistic details for the transformation using the reagents provided. Explain why product 4 is formed rather than 5 under these reaction conditions