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Marketing, case study, The case describes how the Mayo Clinic, one of the most prominent hospitals in the world, engaged designers and built a research institute, the Center for Innovation (CFI), to study the processes of healthcare provision. The case documents the many incremental innovations the designers were able to implement and the way designers learned to interact with physicians and vice-versa.

31 Has human-to-human transmission of the H5N1 avian influenza virus been described?

32 In brucellosis, is it possible to see a brucella agglutination test of more than 1/160 even for years after specific and successful therapy of brucellosis?

33 Please define the terms holoendemic, mesoendemic, and hyperendemic in relation to malaria.

34 You only recommend malarone for malarial prophylaxis when there is a significant chlorquine resistance. Isn't malarone now widely used in travellers going to areas with low resistance.

35 Parenteral vaccination with a killed suspension of Vibrio cholerae is recommended by some - isn't an oral vaccine better?

36 Please suggest possible reasons why Entamoeba histolytica infection associated with bloody diarrhoea is not relieved by treatment with ciprofloxacin and metronidazole 400 mg 2 daily over a 3-week period.

37 Is there a basis for treating patients for filariasis according to the eosinophil count (except for cases of tropical pulmonary eosinophils; TPE)? Filariasis is everywhere in my part of the world; a fluorescent antibody test (FAT) might not be very useful - except when there are very high values.

38 Why do patients who ingest eggs from a tapeworm in contaminated food not develop tapeworms?

39 I have a query about one of the details in the book. You mention that perihepatitis is a feature of gonorrhoeal infection, but other books say that perihepatitis (Fitz-Hugh-Curtis syndrome) is a complication of chlamydial infections. Is there a possibility of perihepatitis in gonorrhoea?

40 In the 7th edition of Kumar and Clark Clinical Medicine, you indicate that there is no benefit in treating the male partner of a woman diagnosed with bacterial vaginosis (BV). As many physicians use the 2 g 1 metronidazole dose, is this unwarranted? Does it differ in women experiencing frequent recurrences of infection?