Hemophilia is a sex-linked bleeding disorder that slows the blood clotting process. In severe cases of hemophilia, continued bleeding occurs after minor trauma or even in the absence of injury. Hemophilia affects 1 in 5,000 male births. In the United States, there are approximately 4,000,000 births per year. Assume that there are equal numbers of males and females born each year.

a) What is the probability that at most 380 newborns in a year are born with hemophilia?

b) What is the probability that 450 or more newborns in a year are born with hemophilia?

c) Consider a hypothetical country in which there are approximately 1.5 million births per year. If the incidence rate of hemophilia is equal to that in the US, as well as the sex ratio at birth, how many newborns are expected to have hemophilia over five years, and with what standard deviation?