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How do neuromodulatory systems such as the dopaminergic, serotonergic, and cholinergic systems regulate mood, motivation, and cognitive function through widespread projections and interactions with neural

How do neuromodulatory systems such as the dopaminergic, serotonergic, and cholinergic systems regulate mood, motivation, and cognitive function through widespread projections and interactions with neural circuits implicated in reward processing, attention, and decision-making? 

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