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Huntington's disease (HD) is due to an autosomal DOMINANT gene. This disease results in deterioration of the nervous system and often symptoms do not

Huntington's disease (HD) is due to an autosomal DOMINANT gene. This disease results in deterioration of the nervous system and often symptoms do not begin until middle age, usually when a person is in their 40's or 50's. Heidi is concerned with whether or not she has inherited the gene for Huntington's disease. Her aunt Alexandra (her mother's sister) was recently diagnosed with Huntington's disease at age 46. Heidi's mother, Ava, died at age 61, and never showed symptoms of Huntington's disease. Heidi's maternal grandparents are Charles and Amelia (parents of Ava and Alexandra). Charles died at age 76 with no signs of Huntington's disease. Amelia died at age 36, giving birth to Alexandra, and was likely too young when she died to exhibit symptoms of the disease if she had it. Heidi's father does not have Charles - Heidi's Amelia - Heidi's maternal grandmother -died at age 36 maternal grandfather - no Huntington's disease Huntington's disease. What are the genotypes of each of the following individuals? Use "H" to represent the allele for Huntington's disease, and "h" to represent the normal (non-Huntington's) allele. Aunt Philip No HD Heidi's mom - Heidi's father no Huntington" disease. Ava Alexandra - Ava has no Huntington's Huntington's disease disease Aunt Alexandra Charles Amelia Heidi 189 Thomas What is the probability that Heidi has inherited the gene for Huntington's disease? Please explain or show your Punnet square for credit. What is the probability that Aunt Alexandra's only child, Thomas, has inherited the gene for Huntington's disease? (Aunt Alexandra's husband, Philip does not have Huntington's disease.) Please explain or show your Punnet square for credit.

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