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If you could please answer in as much detail as possible. I rate quick! Describe the weak (non-covalent) interactions that are so important in determining

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Describe the weak (non-covalent) interactions that are so important in determining the affinity of a drug for its biomolecular target. Be sure to describe the hydrophobic effect in detail and how it is related to the de-solvation penalty that accompanies binding of a drug to its bimolecular target

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