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In a case-control study, exposure status was misclassified as follows: Study Population without Misclassification Cases Controls Exposed 500 500 Unexposed 250 1000 Study Population with

  1. In a case-control study, exposure status was misclassified as follows:
Study Population without Misclassification
Cases Controls
Exposed 500 500
Unexposed 250 1000
Study Population with Misclassification
Cases Controls
Exposed A 250 B 250
Unexposed C 500 D 1250

C. If there is evidence of information bias, is it differential or nondifferential? Explain why by comparing the errors in misclassification of exposure between the cases and controls.

D. If there is information bias, is it towards OR away from the null? Why?

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