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In a study of glioblastoma, 137 affected sig-pairs were recruited. Participants were genotyped for many microsatellite markers across the genome to assess linkage. At
In a study of glioblastoma, 137 affected sig-pairs were recruited. Participants were genotyped for many microsatellite markers across the genome to assess linkage. At one marker, 81 pairs share 2 alleles IBD, 46 pairs share 1 allele IBD, and 10 pairs share 0 alleles IBD. i. What are your null and alternate hypotheses? j. Please calculate MLS. k. Please calculate the appropriate test statistic. 1. What is the critical value of the test statistic? m. What do you conclude?
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i Null hypothesis H0 The marker is not linked to the disease Alternate ...
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Genetics Analysis And Principles
Authors: Robert Brooker
5th Edition
978-0073525341, 0073525340
