In an attempt to solve this problem, Best founded DonorsChoose.org, a website that would match donors directly with New York City public school teachers who needed funding for classroom materials and activities. Simple in its conception, the DonorsChoose.org model actually required a number of systems to insure that teachers posted good projects, that donors could easily choose among projects, and that a link was forged between the donors and students. Best believed that this direct link between donors and classrooms would address "the scarcity and inequitable distribution of learning materials and experiences in our public schools."

11 I am a third-year student nurse and am currently researching a case study based on the biopsychosocial history of a patient who suffers from chronic hepatitis C, which initially occurred as a result of injecting drugs. I am confused about the biological effect of hepatitis: how exactly does it affect the liver?

12 What are the admission criteria for a case of acute viral hepatitis?

13 I would like to know where I can find details on hepatitis B virus (HBV) infection: chronic carrier, asymptomatic [normal liver function tests, HBV DNA/real-time polymerase chain reaction (PCR) 240 copies/mL, core less than 0.1]. Does a patient with such a profile need therapy or fine needle aspiration (FNA) biopsy? What is the possibility of hepatocellular carcinoma (HCC) in such a patient?

14 In chronic hepatitis B virus (HBV) infection, when anti-hepatitis B e antibody (anti-HBe) develops (seroconversion), the antigen disappears and there is a rise in alanine transferase (ALT). However, the graph in your book (K&C 7e, p. 337, Fig. 7.16) seems to show a fall in ALT at this point. Which is correct?

15 Interferon can be used in prophylaxis from hepatitis C after exposure. Could you explain how this can be used, and what degree of success can be expected as a result?

16 What is the latest recommended drug treatment for hepatitis C?

17 Can hepatitis C disease be treated in a carrier state completely by giving interferon?

18 I am a carrier of hepatitis C (HCV) and am going to have antiviral treatment soon. Are the side-effects of antiviral treatment for HCV bound to occur? I am very worried.

19 Besides needle-pricks, how else is it possible to contract hepatitis C from a hepatitis C (HCV)-positive patient? Are the patient's skin/sweat (or other bodily secretions) infectious?

20 What is the risk of infection with hepatitis C from blood splashed into the eyes?