"In retail, Wal-Mart uses vast amounts of data and category analysis to dominate the industry. Harrah's has changed the basis of competition in gaming from building mega-casinos to analytics around customer loyalty and service. Amazon and Yahoo aren't just e-commerce sites; they are extremely analytical and follow a "test and learn" approach to business changes. Capital One runs more than 30,000 experiments a year to identify desirable customers and price credit card offers."(Business Intelligence Definitions and Solutions, Ryan Mulcahy)

31 A 64-year-old woman tells me she has been on hormone replacement therapy (HRT) - oestrogen only following a hysterectomy - for 7 years. She wants to continue with this therapy as she thinks it helps her. How long should I continue prescriptions?

32 Is there a difference between impotence and erectile dysfunction and are the treatments different if they are different conditions?

33 In multiple endocrine neoplasia under screening, you say that family members who are 'at risk' should be screened. What does that mean?

34 You mention that a number of tests can be used in the diagnosis of a phaechromocytoma. Can you say which is the best and do they all need to be done, considering the expense of those investigations?

35 In a patient who is found to be hypertensive, how should we exclude Conn's syndrome?

36 Diabetes mellitus and diabetes insipidus are very different conditions so why are they both called diabetes?

37 I have a young patient who has hirsutism associated with the polycystic ovary syndrome. She has become desperate about her symptoms, which have not been improved by long-term medical treatment with oestrogens, spironolactone and cyproterone. She has asked about whether surgery would help.

38 In a previously fertile patient with infertility secondary to testosterone replacement, how soon after stopping testosterone therapy will he become fertile again? Can reduced fertility and hypogonadism be treated other than with testosterone replacement therapy?

39 Why is the 'insulin-like growth factor' (released from the liver in response to the growth hormone) so called, although it opposes the effects of insulin?

40 Does hyperprolactinaemia cause gynaecomastia?