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In stereochemistry, which statement correctly describes the concept of topicity and its application in the assignment of stereochemical relationships? A) Topicity refers to the spatial

In stereochemistry, which statement correctly describes the concept of topicity and its application in the assignment of stereochemical relationships? A) Topicity refers to the spatial relationship between atoms in a molecule and is used to assign R/S configuration to chiral centers. B) Homotopic atoms or groups in a molecule exhibit identical chemical shifts in NMR spectroscopy and their replacement leads to achiral molecules. C) Enantiotopic atoms or groups in a molecule are mirror images and their replacement always results in diastereomers. D) Distopic atoms or groups in a molecule are always located in different environments and their replacement leads to enantiomers. Don't use chat gpt.

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