In such projects, the Molecular Allies division brings with it a "wealth of experience and expertise in target identification, screening, synthesis, molecular design and informatics" (Annual Report 1997). More importantly, it brings with it a network of contacts through which it can access the skills of leading edge researchers. There are two strands to this network. The first is access to university researchers. This is a key element of the division's original guiding principle.

Question 41 What is the meaning of the international normalized ratio (INR) blood test? Question 42 What is the cause of moderate thrombocytopenia in Bernard-Soulier syndrome? It is a qualitative defect not a quantitative platelet disorder.

43 What is new about thrombopoietin?

44 What is the rationale behind the use of desmopressin in bleeding disorders?

45 What effect does the contraceptive pill have on the blood fibrinogen level and on blood coagulability?

46 Does standard (unfractionated) heparin in doses of 10 000-15 000 units/day need monitoring?

47 Is there an antidote for low-molecular-weight heparin (LMWH)? Can Enoxaprin be used?

48 1. What is the mechanism of the action of aprotinin? 2. What is the therapeutic window for aprotinin? 3. In a case of haemorrhagic stroke, how many days should aprotinin be prescribed for and what is the recommended dosage?

49 My question is, what are thrombophilia scan tests? Can we use these in patients on anticoagulant therapy?

50 In thromboembolic disorders, how is clopidogrel superior to aspirin?