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What is the time and volume requirement for the 99% removal of Metoprolol, selective receptor blocker medication used to treat high blood pressure, from

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What is the time and volume requirement for the 99% removal of Metoprolol, selective receptor blocker medication used to treat high blood pressure, from the cardiovascular unit of a hospital wastewater effluent? Ozone will be used as the oxidizer in a tubular ( 050 cm) reactor for a 10 m daily wastewater discharge (removal rate constant is calculated as 8.7x104 L mol).

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