In the beads on a string model, the bead is made up of __________

a) 6 histone proteins

b) 8 histone proteins

c) 6 histone proteins and DNA

d) 8 histone proteins and DNA

2. The unpacked stretches of DNA are the extra chromosomal load found in the eukaryotic genome.

a) True

b) False

3. How many types of histone molecules are found in nature?

a) 3

b) 4

c) 5

d) 6

4. Nucleosome is made up of __________

a) DNA, histone core protein

b) DNA, histone core protein, linker H1

c) RNA, histone core protein

d) RNA, histone core protein, linker H1

5. Histones have a high content of negatively charged amino acids.

a) True

b) False

6. With respect to assembly of every core histone which of the following is wrong?

a) A conserved region

b) Histone fold domain

c) Disc shaped structure

d) 2 helices and an unstructured loop

7. Which of the following histone pairs forms tetramers in solution?

a) H1, H2A

b) H2A, H2B

c) H2B, H3

d) H3, H4

8. With respect to the "tails" of the histone molecules which of the following is not true?

a) N - terminal extension

b) Lacks defined structure

c) Required for the association of nucleosome

d) Sites for extensive modifications

9. How many contacts are observed between the DNA and the histone core protein?

a) 14

b) 21

c) 54

d) 17