In this difficult we will see that the least squares attack of a line is only the MLE accepting the blunder terms are ordinarily dispersed.

For bivariate information (x1, y1), . . . ,(xn, yn), the basic direct relapse model says that yi is an arbitrary worth produced by an irregular variable

Yi = axi + b + ?i where a, b, xi are fixed (not arbitrary) qualities, and ?i is an irregular variable with mean 0 and fluctuation ?2.

(a) Suppose that each ?i ? N(0, ?2). Show that Yi ? N(axi + b, ?2).

(b) Give the equation for the pdf fYi (yi) of Yi.

(c) Write down the probability of the information as a component of a, b, and ?

Measurements show that under 40% of all emergency clinic based doctors are utilized as full-time staff by the emergency clinics where they practice, an impression of the profoundly instilled culture of expert self-sufficiency in medication and the profoundly held conviction of care experts that their definitive duty is to singular patients. These conditions have presented huge difficulties to the authority of medical services the executives in numerous associations, regularly making disunity and question between medical care experts and medical services the board. Different difficulties to the board incorporate the progressive idea of the wellbeing callings and inborn protection from group based consideration, critical administrative and managerial prerequisites (e.g., controlled substances, biohazardous garbage removal, patient security, wellbeing, and so on), and medical services installment/repayment systems that give pretty much nothing, assuming any, motivators for medical services associations to put resources into non-income creating resources, like data/correspondences advances and interaction the executives apparatuses.

QUESTIONS

1. Essentially, the G various __________ locales for a compound in a specific __________, absorption is acted in __________ stages. State how the starter absorption should be. For what reason is the absorption around there?

2. Histones involve a limit of negative charged amino corrosive components.

Decide if the surmising is legitimate or invalid and elaborate.

3. DNA, histone center protein, linker H1 are constituents of?

4. Support the accompanying.

Supplement limitation areas can be introduced near the current requirement area by means of mutagenesis.

5. Decide why the derivation underneath is defective concerning each base histone.

6_______ and _______ histone initially creates _______ at that point they come together to frame a _______ with two atoms of each. What unfolds on the inverse?

7. Give the personality given to a chain of dispensed with segments that other DNA particles of equivalent length go about as intermediary for.

8. As shown in human life structures, _______apparatus are applied when the pace of medication scattering from the hardware is _____________ comparative with the pace of medication ______ by means of the layer _______. State one attribute of solid gadgets.

9.Identify the two arrangements of network device in drug-biotechnology.

10. Making deduction from science, the ___________ DNA ___________ to which the ___________ factors are bound are perceived as ___________ components. Express the conditions under which the component can tie.

11. How can it be that the limiting of the administrative protein at significant distance can in any case depict their effect?

1. (15 points) Cryptocurrency traders pay close attention to daily trends in Bitcoin value. On any given day, the Bitcoin values can be trending-up, trending-down, or remain sta- ble. Traders have observed that daily trends in Bitcoin value can be modeled by a Markov chain. Following a day when value is trending-up, the next day value can be trending-up again with probability 0.4 or trending-down with probability 0.1. After a day when value is trending-down, the next day value can be trending-up with probability 0.7 and it is twice likely to remain stable than trending-down. If the current trend is stable, the next day it will be trending-up with twice probability than trending-down, and it will remain stable with probability 0.1. (a) (5 points) Define the states and transition probability matrix P. (b) (5 points) Assume you will start trading a specific type of Cryptocurrency on Monday. On Monday it is equally likely for Bitcoin value to be trending-up or trending down and it is twice as likely to be stable than to be trending-up (or trending down). What is the probability that on Thursday of the same week the Bitcoin will be down-trending? (c) (5 points) Assume that trader Jane trades an equal number of coins every day. On the day that Bitcoin value is down-trending Jane loses $500. On the day the bitcoin value is stable, Jane breaks even, and when trending up, Jane makes a profit of $1000. On the long run, what is Jane's average daily profit?Question 3: (5+5+5+5marks) If approximately 2% of the people in a room of 200 people are left handed find the probability that: a) Exactly 3 people there are left handed. b) At least one there is left handed. c) Exactly 5 people there are left handed by using Poison approximation. d) Find the variance of the probability distribution.Question 2 The number of patients admitted to the intensive care unit (ICU) at Hospital Pantai on any given day has a Poison probability distribution with mean equal to five patients per day. a) Write the probability distribution for the number of patients admitted to the ICU at Hospital Pantai. [2 marks] b) Find the probability that the number of people admitted to the ICU on a particular day is at least three. [4 marks] c) What is the probability that ten people admitted to the ICU for a two-day period? [4 marks]7. Records show that the probability is 0.0012 that a person will get food poisoning at a food fair in lowa. (a) Use the Poisson approximation to the binomial distribution to find that at most 2 of 1,000 persons attending the fair will get food poisoning. Use the Poisson formula P(x; A) = (X" e")/x!! (b) Use the Poisson table, and explain how you are deriving the probability