Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

Investigators based their hypothesis generation about the association between oral contraceptive use and ovarian cancer on the relationship between ovarian cancer and pregnancy. Pregnancy was

Investigators based their hypothesis generation about the association between oral contraceptive use and ovarian cancer on the relationship between ovarian cancer and pregnancy. Pregnancy was described as potentially protective against ovarian cancer. The investigators were interested in seeing whether the association between oral contraceptive use and ovarian cancer differed for women of different parity (number of babies delivered). To investigate this, they compared four different studies. Table 2 presents results from 4 studies (these data are fictitious) for the crude OR and the stratum-specific associations. For the purposes of this exercise, do not worry about statistical significance.Also assume that parity is not on the causal pathway between oral contraceptive use and ovarian cancer.

Table 2. Comparison of crude and stratum-specific estimates in four different studies

Study Crude OR Parity = 0 Parity > 1
Escargots et al 1.25 0.87 0.86
Baguette et al 0.78 0.77 0.76
Champagne et al 0.95 1.97 1.98
Barnaise et al 0.56 1.98 0.23

Based on the data shown in Table 2, complete the following table to indicate whether there is confounding or effect modification for each study.

Study Effect Modification Confounding
Escargots et al

8. a. Yes

b. No

9. a. Yes

b. No

Baguette et al

10. a. Yes

b. No

11. a. Yes

b. No

Champagne et al

12. a. Yes

b. No

13. a. Yes

b. No

Barnaise et al

14. a. Yes

b. No

15. a. Yes

b. No

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Discrete Mathematics With Applications

Authors: Susanna S Epp, Robert Gatewood,

4th Edition

1133168663, 9781133168669

More Books

Students also viewed these Mathematics questions

Question

b. Is it an undergraduate or graduate level course?

Answered: 1 week ago