-Describe the life cycle of HIV according to Fig. 1.5, specifically the specific functions of gp120, reverse transcriptase, protease, integrase, CCR5 and CD4 -Describe how AZT inhibits reverse transcriptase from acting at the molecular level -Describe the four tenets of natural selection and how they are met when an HIV-infected person takes AZT -Describe what HIV trait(s) are under natural selection when a person begins AZT -Know approximately how old HIV is, what virus it is most closely related to, when the original HIV strain likely moved into humans, and how we obtained this information -Know what potential humans have to evolve resistance to HIV, in terms of how variation in CCR5 and CD4 may be involved