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mainly need help on question 2 (batch reaction times) Background The hydrolysis of Penicillin G (Pen-G) yields phenylacetic acid (PAA) and 6-amino-penicillanic acid (6APA )
mainly need help on question 2 (batch reaction times)
Background The hydrolysis of Penicillin G (Pen-G) yields phenylacetic acid (PAA) and 6-amino-penicillanic acid (6APA ) (M=216g/mol), the latter being an intermediate for a wide range of semi-synthetic antibiotics. The react) can be catalyzed in an aqueous solution with a strong acid, a strong base or an enzyme called Pen- G acylase. Phemylacetic acid 6-Amino-pericillanic acid Pon-G) (PAA) (G-APA) On the order of 10,000 tons of 6-APA is produced worldwide on an annual basis, using batch processes that are of moderate scale. The production-scale reactor available for your hydrolysis process is constructed from stainless steel, with a maximum liquid volume of 20m3 and operating temperatures between 35C and 85C. Design Calculations Show all work on a separate page and report the final values below. Upload work with this answer sheet upon submission. If a calculation is repeated multiple times, only one example calculation needs to be shown as work. 1. Rate Expression Development Generate an expression for the rate of Pen-G hydrolysis as a function of reagent concentrations by modelling the initial rate data provided in Table 1. This rate expression should have the general form: Rate=k[PenG]m[KOH]n Pay particular attention to the units for each parameter of your kinetic model. Report your parameters below and complete the last two columns of Table 1, including the units in the header row. m=1n=11 Table 1 Laboratory Data 2. Batch Reaction Times Use your rate expression to predict the time in heurs that is recuired to achieve 504 . 9556 and 9994 conversion of Pen-G to 6.APA for a batch reaction that is operated with [PPenG]. hit =0.12M,PH=1F,T=70C. Assume that pH remains essentially constant throughout the process. Recominend an overali reactiochane at this condition and calculate the mass of G-APA that the proceis will provide fram a single 20m3 bateh. Report with wnits: conversion =50%,95%,79.4% tresct opansin mis4sin= Please submit your completed essignment with work to OnQ at VR A ssignment Part 1. Design Prototyping ond resting" submission folder Step by Step Solution
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