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managerial accounting.The employment or workforce strategy is not always articulated in one or more written documents, but covers the dimensions, sources and supply and any

managerial accounting.The employment or workforce strategy is not always articulated in one or more written documents, but covers the dimensions, sources and supply and any changes required to the size, shape and nature of the workforce and its contractual and psychological relationship with the organisation. This is where strategic workforce planning now sits in the process of aligning employment plans with business needs and as our case studies illustrate, with such a tight labour market in the UK, employers across all sectors and sizes at last appear to be taking workforce planning seriously.

Answer 1 Opsoclonus is characteristic of the paraneoplastic syndrome. It describes rapid, chaotic, conjugate, spontaneous eye movements that distort ocular fixation. It is associated with ataxia and other brain stem disturbances.

Answer 2 It can do but a high LDH also occurs with haemolysis, liver disease and myocardial infarction.

Answer 3 No; the ESR will usually be raised but this is by no means invariable.

Answer 4 Folinic acid, not folic acid, is used to counteract the folate antagonist action of methotrexate and should be given 24 hours after the methotrexate and not at the same time.

Answer 5 No. Imatinib is first line therapy. Answer 6 Low-grade gastric MALT lymphomas restricted to the mucosa or submucosa are often treated successfully by H. pylori eradication but others require surgery and chemotherapy. Try eradication therapy initially. CD2 is associated with T and natural killer (NK) cells; MALT lymphomas are B cell lymphomas.

Answer 7 'Site' and 'organ' mean the same most of the time. Sometimes, however, the site is clear (e.g. a mass in the epigastrium) without it being very obvious which organ is involved.

Answer 8 Lymphomas are divided histologically into: Hodgkin's lymphoma: characteristically has Sternberg-Reed cells, together with a mixture of lymphocytes and histiocytes. Non-Hodgkin's lymphoma: does not have Sternberg-Reed cells but does have lymphoid tissue of various types depending on the type of lymphoma (see K&C 7e, Table 9.20, p. 480). Further reading Jaffe ES et al (eds) (2001) WHO Classification of Tumours. Pathology and Genetics of Tumours of Haemopoietic and Lymphoid Tissues. Lyon: IARC Press. Malignant disease 9 83

Answer 9 Some lymphomas secrete 1,25-dihydroxycholecalciferol, which will raise the serum calcium level.

Answer 10 No; an X-ray of the area of pain, e.g. the spine, would be the best test but a full skeletal survey, which would of course include the skull, is usually carried out in a patient suspected of having myeloma.

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