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Many clinical trial protocols include plans to compensate participants for their contribution to the research. According to FDA's information sheet Payment and Reimbursement to Research

Many clinical trial protocols include plans to compensate participants for their contribution to the research. According to FDA's information sheet Payment and Reimbursement to Research Subjects, participant payment is a recruitment incentive and "is not considered a benefit that would be part of the weighing of benefits or risks." Additionally, in its Informed Consent FAQs OHRP states that "remuneration to subjects may include compensation for risks associated with their participation in research and that compensation may be an acceptable motive for agreeing to participate in research

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