Margaret owned an antique store that specialised in rare porcelain dolls. When she

opened the business in 1989, it was at a shop in an eastern suburb of Melbourne. In 1999

she started to advertise on the Internet and by 2006 the business had grown to the point

where she needed help to keep the business going. After a family discussion one night at

the kitchen table in July 2006, it was agreed that Margaret would probably keep the

business going for another couple of years and then retire. Emily, her youngest daughter

and aged 16, would work in the shop as long as was needed and in return, she would

receive any unsold dolls. When Margaret retired at the end of 2009, she decided that she

would give the unsold stock to charity and they could auction it and keep the proceeds.

Advise Emily.

31 What is the cause of Pott's disease?

32 One thing that often baffles me is that patients with systemic lupus erythematosus often suffer recurrent thrombosis due to lupus anticoagulants (antiphospholipid syndrome). How can an anticoagulant cause thrombosis?

33 Are elevated homocysteine levels an independent risk factor for progression of systemic lupus erythematosus (SLE)/scleroderma? Kindly suggest some references if possible.

34 1. What are the indicators of remission in systemic lupus erythematosus (SLE)? Is it the normalization of erythrocyte sedimentation rate (ESR) and the disappearance of antinuclear antibodies (ANA) and other antibodies, or is it clinical improvement? 2. During remission of SLE, do fANA and other antibodies disappear?

35 When should the use of cyclophosphamide in systemic lupus erythematosus (SLE) be commenced? What is the correct and safe dosage of cyclophosphamide?

36 1. Given the benefits of dexamethasone, which lacks any mineralocorticoid activity, why is this not prescribed in your book for diseases that require long-term steroid therapy, such as systemic lupus erythematosus or giant cell arteritis? 2. Does dexamethasone have more serious adverse effects than prednisolone? Why is it not generally preferred?

37 Would an elevated C-reactive protein (CRP) level, in association with a high erythrocyte sedimentation rate (ESR) and in the absence of infection and serositis, exclude the diagnosis of systemic lupus erythematosus?

38 How do steroids precipitate a crisis in patients with systemic sclerosis?

39 Are neck and face muscles commonly affected in poly- and dermatomyositis? Does this differ from the muscles that are affected with myasthenia gravis?

40 1. In dermatomyositis, what is the shawl sign? 2. How frequently is dermatomyositis associated with Gottron's papules?