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Mass spectrometry is an analytical technique used to determine the mass-to-charge ratio (m/Z) of ions, molecules, and molecule fragments. The most common application of this

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Mass spectrometry is an analytical technique used to determine the mass-to-charge ratio (m/Z) of ions, molecules, and molecule fragments. The most common application of this is to identify the molecular weight of an analyte and is possibly the most frequently used analytical chemistry technique in the pharmaceutical and fine chemical industries. Detection Faraday collectors {m/Z) = 46 {m/Z) = 45 (m/Z} = 44 current magnet X amplifiers ratio output lon source Figure 1. A simplified diagram of a mass spectrometer. In this instance, the ions being detected are CO2+ {m/Z) = 44, 13CO+ {m/Z) = 45, and 4CO2+ {m/Z} = 46. Mass Spectrum - Unknown #8 62 100 80 60 Relative Intensity 40 64 27 49 20 61 26 28 25 35. 32 3088 1 LA 30 40 14 98 100 102 51 478 ill 59. 10 20 50 60 70 80 90 100 m/z m 11 Proposed Fragment 14 26 27 28 35 49 51 Rel. Intensity 0.7 10 20.3 6.1 4.6 20.2 6.6 12.7 100 13.9 61 33 62 63 64 98 100 102 8.2 5.2 0.8

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