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membrane diameter= 50nm pore diameter = 5nm 2. Scopolamine is a medication used to treat motion sickness and postoperative nausea and vomiting. One way to
membrane diameter= 50nm
2. Scopolamine is a medication used to treat motion sickness and postoperative nausea and vomiting. One way to deliver this drug is through a small patch placed in the hairless region behind the ear. Typically, you have 1 mg of this drug (molecular weight = 303 g/mol) loaded into each patch (a circular piece of material - 1 cm in diameter and -100 micron (0.1 mm) in thickness. It is ready absorbed by the skin, with a partition coefficient (concentration within skin/concentration in patch, at equilibrium) of 5000. If the diffusivity of scopolamine within skin/tissues is 2 x 10-5 cm/s, calculate (a) the initial flux (at =0.01) of scopolamine into the skin [10 points) (b) the time needed for the flux to drop by 50% from its value at 0.01s [20 points) (c) the concentration imm inside the body at the time obtained in part (b) erfa [10 points) Mem SO diam pore diameter = 5nm
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