Metabolic Acidosis/Alkalosis Excessive ingestion of bicarbonate Rarely, excessive administration of bicarbonate IV or ingestion of bicarbonate in antacid (such as Tums) adds excess bicarbonate into the blood. Effect on blood: [HCO3] Overdose of Tums ACIDOSIS or ALKALOSIS Number of unbuffered H+ in blood pH (circle one) Digestive problems- Excessive diarrhea Abnormal loss of bicarbonate from the body can occur during severe diarrhea Excessive Effect on blood: [HCO3] ACIDOSIS or diarrhea Number of unbuffered H+ in blood pH ALKALOSIS (circle one) Digestive problems- Excessive vomiting Gastric juice is acidic and any disease process in which gastric contents are lost from the body represents a loss of hydrogen ions. This includes excessive vomiting. Excessive ACIDOSIS or ALKALOSIS vomiting Effect on blood: [H+] pH (circle one) Renal failure Failure to regenerate bicarbonate and excrete hydrogen ions causes pH imbalance. Effect on blood: [H+] Effect on blood: [HCO3 ] ACIDOSIS or Renal failure pH ALKALOSIS (circle one)