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My hypothesis about the below Tables, is that the Mechanically gated ion channels in this neuron are voltage gated, mechanical and selectively permeable to K+

My hypothesis about the below Tables, is that the Mechanically gated ion channels in this neuron are voltage gated, mechanical and selectively permeable to K+ ions. The MACs are open and voltage clamped.

What is a follow up experiment to to verify this hypothesis?

image text in transcribedimage text in transcribed

Ion Species x Membrane Resting Potential VM @ 20 C Nat K+ Ca2+ Mg2+ CI VM Extracellular Intracellular Equilibrium Concentration Concentration Potential [X]OUT [X]IN Ex @ 20 C 260 mm 35 mM + 50.7 mv 8 mm 340 mm - 94.7 mV 20 mm 0.1 mm +66.9 mV 60 mm 0.2 mm + 72.0 mV 560 mm 60 mm - 56.4 mV - 58.4 mV Table 1: Intracellular and extracellular ion concentrations and resulting equilibrium potentials and membrane resting potential at 15 C. VM(mv) - 100 - 80 -60 - 40 -20 0 + 20 +40 +60 +80 + 100 IR (PA) -530 - 350 - 250 - 175 -110 - 70 - 40 - 25 - 8 + 5 + 8 Table 2: Raw Data for the experiment shown in figure 1. Ion Species x Membrane Resting Potential VM @ 20 C Nat K+ Ca2+ Mg2+ CI VM Extracellular Intracellular Equilibrium Concentration Concentration Potential [X]OUT [X]IN Ex @ 20 C 260 mm 35 mM + 50.7 mv 8 mm 340 mm - 94.7 mV 20 mm 0.1 mm +66.9 mV 60 mm 0.2 mm + 72.0 mV 560 mm 60 mm - 56.4 mV - 58.4 mV Table 1: Intracellular and extracellular ion concentrations and resulting equilibrium potentials and membrane resting potential at 15 C. VM(mv) - 100 - 80 -60 - 40 -20 0 + 20 +40 +60 +80 + 100 IR (PA) -530 - 350 - 250 - 175 -110 - 70 - 40 - 25 - 8 + 5 + 8 Table 2: Raw Data for the experiment shown in figure 1

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