Nigel, a freshman in college, attends a frat party. He is introduced to different types of drugs and unfortunately gets addicted to Methamphetamine (Meth). Over the next two years, Nigel experiences long-term effects such as erratic mood fluctuations, aggressive or violent behavior, problems with motor control, and problems in his thinking ability. Based on his long-term side effects, which two neurons has Nigel most likely damaged by using this Methamphetamine?