Now you are being asked to use the operative principle of diffusion that resulted in eqns $2-4,$ to determine

possible reduction in solute concentration.

$CsB\frac{i}{C}$sBi $=$exp$[QsB\frac{t}{V}t(exp(-k\frac{A}{Q_B})-1)]$

$if$ one defines $B=>$exp$(-k\frac{A}{Q_B})$

where $K=>$ overall mass transfer coefficient $(c\frac{m}{m}in)$;$A=>$ membrane area $(c{m}^2)$;$Q_B=$ blood flow

$CsB\frac{i}{C}$sBi$=$exp$[QsBt\frac{-1}{V}t]$

$($a$)$ For appropriate values of $($nominal$)$ and for $Vt=50L,Qb=200m\frac{l}{m}in,$ please determine the

reduction in $Cs(t)$ for $t=1hr,4hrs$ and $8hrs.$

$($b$)$ For a given value of $,$ what membrane area would be needed to achieve the reductions calculated

in $Cs(t)$; where the total membrane resistance $R_T=45mi\frac{n}{c}m,K=\frac{1}{R_T}$ for a blood flow rate

$(Q_B)$ of $200m\frac{l}{m}in.$

$($c$)$ From the table below, please calculate the reduction in the concentration of a solute i when using

a Baxter Revaclear$-400$ hemodialyzer with a blood flow rate of $200m\frac{l}{m}in$ for treatment times of

for $t=1hr,2hrs$ and $4hrs.$