Onset Distribution within lungs Pathophysiology Causative agent Streptococcus pneumoniae Signs and symptoms. Lobar Pneumonia Treatment Interstitial Pneumonia Influenza virus Sudden and acute Mycoplasma Insidious Variable All of one or two lobes Scattered small patches Diffuse throughout lung Interstitial inflammation around alveoli Necrosis of bronchial epithelium Variable fever, headache Inflammation of alveolar wall and leakage of cells, fibrin, and fluid into alveoli causing consolidation High fever and chills Productive cough with rusty sputum Rales progressing to absence of breath sounds in affected lobes Antibacterial medication in combination with fluids; drugs to reduce fever; and oxygen Pneumococcal vaccine is recommended for the elderly and those at risk for other disease Bronchial Pneumonia Multiple bacteria Inflammation and purulent exudate in alveoli often arising from prior pooled secretions or irritation Mild fever Productive cough with yellow-green sputum Dyspnea Antibacterial medications (DOP